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Pharmacology Watch: Two New Drugs Approved for Treatment of Hepatitis C
In this issue: Two new drugs for treatment of hepatitis C; NSAIDs and myocardial infarction risk; AIM-HIGH clinical trial stopped; and FDA actions.Abstract & Commentary: Supplemental Oxygen Administration in the Morbidly Obese: When Less is Better
Current guidelines for the use of emergency oxygen recommend its judicious use in patients with obesity-associated hypoventilation (OAH) in order to avoid worsening hypercarbia, but these guidelines have largely been based on anecdotal clinical experience rather than systematically collected evidence.Abstract & Commentary: Sleep Apnea and Perioperative Complications After Noncardiac Surgery
In this study of a large administrative database, the incidence of selected complications in patients diagnosed with sleep apnea (SA) was compared to that in patients undergoing similar surgical procedures who were not diagnosed with SA.Clinical Briefs in Primary Care supplement
Special Feature: Use of Therapeutic Hypothermia After Cardiac Arrest
When patients sustain a sudden cardiac arrest, they require immediate life-saving therapies to restart cardiac function and prevent secondary anoxic brain injury.Abstract & Commentary: Should We Look at the Stomach with Ultrasound Prior to Intubation?
Bedside ultrasound is increasingly being performed in the intensive care unit (ICU) for a variety of purposes including guiding volume resuscitation, central line placement, and marking pleural fluid collections for drainage.Abstract & Commentary: Does COPD Worsen Outcomes When Mechanical Ventilation is Required for Other Reasons?
Rodríguez and colleagues report on a prospectively enrolled cohort of 235 consecutive patients admitted to two ICUs in Spain who required mechanical ventilation for at least 48 hours and had indications for ventilatory support other than respiratory infection or acute exacerbation of chronic obstructive pulmonary disease (COPD).Pharmacology Watch: Women's Health Issue — Adverse Medication Effects
In this issue: Calcium supplements and MI; birth control pills and VTE; ACE inhibitors and breast cancer risk; spending on pharmaceuticals; and FDA actions.Clinical Briefs in Primary Care supplement
Abstract & Commentary: Long-Term Psychological Effects of Critical Illness
The authors investigated whether intra-ICU clinical psychological support could impact anxiety, depression, and post-traumatic stress disorder (PTSD) rates in patients 1 year after ICU discharge.