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Capitalizing on data from a rather homogenous population of breast cancer patients treated with a single chemotherapy regimen (FEC), Jenkins and Freeman found that pretreatment absolute neutrophil and absolute lymphocyte counts, examined together, were highly predictive of risk for all neutropenic events, including febrile neutropenia, dose delays, and overall reduced dose intensity over the six cycle course of treatment.

Pre-Treatment CBC and the Prediction of Myelotoxicity