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This meta-analysis of studies examining the efficacy of systemic corticosteroids for preventing laryngeal edema following extubation concludes that this treatment is effective. This result differs from those of several previous meta-analyses, and raises practical issues such as whether extubation should be delayed for at least 12 hours after a patient passes a spontaneous breathing trial and qualifies for extubation so that a course of steroids can be given.

Steroids to Prevent Extubation Failure?