Sildenafil Improves Insulin Sensitivity
Chronic use of sildenafil (Revatio, Viagra) improves insulin sensitivity in prediabetics, according to a new study. In a randomized, double-blind, placebo-controlled study, subjects were randomized to treatment with sildenafil 25 mg three times a day or matching placebo for 3 months. Twenty-one subjects completed each treatment arm. After 3 months, the insulin sensitivity index was significantly greater in the sildenafil group compared to the placebo group (P = 0.049). Sildenafil also decreased the urine albumin to creatinine ratio, an effect that persisted 3 months after discontinuation. Further study is needed to see if sildenafil can prevent diabetes in high-risk individuals, but these early results are promising (J Clin Endocrinol Metab doi: 10.1210/jc.2015-3415).
Chronic use of sildenafil (Revatio, Viagra) improves insulin sensitivity in prediabetics, according to a new study.
Subscribe Now for Access
You have reached your article limit for the month. We hope you found our articles both enjoyable and insightful. For information on new subscriptions, product trials, alternative billing arrangements or group and site discounts please call 800-688-2421. We look forward to having you as a long-term member of the Relias Media community.