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Since the introduction of the 3-weekly CHOP (cyclophosphamide, adriamycin, vincristine, prednisone) chemotherapy 25 years ago, many efforts have been undertaken to improve the efficacy of multicycle polychemotherapy for patients with aggressive lymphoma.

Practicability and Acute Hematological Toxicity of 2- and 3-Weekly CHOP and CHOEP Chemotherapy for Aggressive NHL