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Over the last few decades, technology has existed to evaluate the cytotoxic effects of single-agent and combination chemotherapy on cancer cell lines derived from an individual patient's tumor specimens. However, investigators and clinicians have been frustrated as the fruit of this technology—a reliable and reproducible assay to help them treat their patients with the agent or agents most likely to benefit them—has yet to be proven.

Special Feature: Chemotherapy Sensitivity/Resistance Assays in Gynecologic Cancer: Are We There Yet?