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Murine typhus is an acute zoonotic infection caused by Rickettsia typhi, an obligate-intracellular Gram-negative bacterium belonging to the typhus group of rickettsiae. R. typhi infections occur worldwide, particularly in warm, humid coastal environments of the tropics; in the U.S., autochthonous transmission also occasionally occurs in Hawaii, Texas, and California. The rat flea, Xenopsylla cheopis is generally considered the primary vector.

Murine Typhus in Returned Travelers