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The incidence of chicken pox has decreased dramatically in the United States since implementation of a universal vaccination program in 1995. However, the question of whether or not there is waning immunity to varicella after one dose of vaccine led Chaves and colleagues to investigate the incidence of varicella in individuals vaccinated with one dose of varicella zoster virus (VZV) vaccine between 1995 and 2004.

Waning Vaccine-Induced Immunity to Varicella