Articles Tagged With: Biomarkers
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Pharmacogenetics in Primary Care: An Update
Advancements in the area of personalized medicine and understanding how one’s genetics affect health outcomes is an evolving science. The addition of pharmacogenetic testing to the armamentarium of primary care providers presents an opportunity to improve patient care.
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Dementia Update
Dementia is a common and growing problem that is associated with significant caregiver burden and immense cost. A growing focus on disease prevention and management of risk factors in mid-life is vital to attempt to mitigate the daunting impact of this illness on patients, caregivers, and the healthcare system as a whole.
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Amyloid, Tau, Neurodegeneration Diagnostic Framework to Predict Memory Decline Before the Onset of Dementia
In a population-based longitudinal study of older individuals without dementia, the inclusion of imaging biomarkers for amyloid, tau, and neurodegeneration modestly improved the ability to predict memory decline compared to a model that only used clinical data and APOE genotype.
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Cholecystokinin as a Biomarker Linking Metabolic Function to Alzheimer’s Disease
In a study cohort from the Alzheimer’s Disease Neuroimaging Initiative, cerebrospinal fluid levels of cholecystokinin were associated with better outcomes that may reflect compensatory protection as Alzheimer’s disease pathology progresses. However, because of significant study limitations, these findings need to be validated in additional studies.
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Predicting the Risk of Mild Cognitive Impairment Using Imaging Biomarkers
In this population-based study, researchers used imaging biomarkers of amyloid and neuronal injury to estimate an absolute risk of mild cognitive impairment in the elderly.
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Salivary microRNA as Biomarker to Predict Prolonged Concussion Symptoms
In a prospective cohort study of pediatric patients, aged 7 to 21 years, diagnosed with concussion, salivary microRNAs were found to be a potential biomarker for predicting prolonged concussion symptoms.
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Serum Tau as a Reliable Biomarker of Outcome After Cardiac Arrest
Currently, there are no reliable and readily available biomarkers to assist in determining prognosis for neurological recovery after cardiac arrest, but serum tau measurements hold promise for the future.
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Tau as a Biomarker of Acute and Chronic Traumatic Brain Injury
The ongoing search for reliable biomarkers of traumatic brain injury repeatedly has demonstrated the reliability of using plasma phosphor-tau levels to help distinguish injury from normal, and severe injury from mild injury.
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Prostate-Specific Membrane Antigen Levels in Sera as a Possible Biomarker for Prostate Cancer