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Clinical Briefs in Primary Care Supplement

Appropriate Utilization of ICDs

In this paper, Packer et al report on the modes of death in patients in the Sudden Cardiac Death-Heart Failure Trial (SCD-HeFT).

ACE Inhibitors and CABG Outcomes

The preoperative use of angiotensin-converting enzyme inhibitors (ACEI) with coronary artery bypass graft (CABG) surgery is controversial. Thus, these investigators from the United Kingdom performed a retrospective, observational study of patients undergoing isolated CABG who did not have cardiogenic shock.

Statins and Bypass Surgery — Is There a Benefit?

Statins have been used in an increasing number and variety of conditions. This large, 10-year cohort study from John Hopkins Neurology Department and Cardiac Surgery Group uses a post-hoc analysis to examine the issue of whether statin use prior to Coronary Bypass Graft Surgery (CABG) would decrease post-op morbidity, specifically stroke and encephalopathy, as well as cognitive decline.

Pharmacology Watch

Statin and niacin increase HDL-C, omeprazole reduces effectiveness of clopidogrel, darbe-poetin increases risk of stroke, statins decrease risk of gallstone disease, FDA Actions

Bi-ventricular vs. RV Apical Pacing

Yu et al report a multi-center trial evaluating the relative benefits of right ventricular apical pacing compared to biventricular pacing in patients with a standard indication for pacing and a baseline preserved left ventricular ejection fraction.

Pharmacology Watch

Results from a Phase 3 study of dabigatran, intensive lipid-lowering in CVD, H1N1 vaccine dosing and efficacy, and FDA Actions

FDA and Medical Devices

In this paper, Dhruva et al examine the types of studies that were involved in premarket approval (PMA) of cardiovascular devices by the FDA over a seven-year period.

Value of VT Ablation Prior to ICD Placement

The ventricular tachycardia ablation in coronary Heart Disease (VTACH) study tested the hypothesis that mapping and prophylactic catheter ablation of ventricular tachycardia prior to implantable cardioverter defibrillator (ICD) insertion in patients with hemodynamically stable ventricular tachycardia (VT) would improve clinical outcomes.

Off-pump Coronary Bypass Surgery vs. Traditional CABG — Is There a Winner?

Coronary revascularization without cardiopul-monary bypass has become quite successful, in part because of the belief that off-pump coronary bypass procedures are safer than on-pump surgery.

Articles Tagged With: Cardiology