Articles Tagged With: alteplase

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Thrombolysis for ‘Wake-up’ Stroke

In patients with acute ischemic stroke of unknown time of onset, a mismatch between diffusion-weighted imaging and FLAIR imaging in the region of ischemia resulted in better functional outcome if treated with intravenous alteplase, but with more symptomatic intracranial hemorrhages.

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Tenecteplase vs. Alteplase for Ischemic Stroke

In a recent trial, treatment with tenecteplase before thrombectomy was associated with a higher incidence of reperfusion and better functional outcome than alteplase if administered to patients with ischemic stroke within 4.5 hours of symptom onset.

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Acute Ischemic Stroke Due to Large Vessel Occlusion

Acute stroke reperfusion therapies have led to significant reduction in the morbidity and mortality associated with ischemic strokes due to large vessel occlusion. This article will discuss the prevalence, mechanism, diagnosis, and treatment options of acute ischemic stroke due to large vessel occlusion.

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