Articles Tagged With: antibiotics
-
WHO Updates STI Treatment Guidance Due to Growing Antibiotic Resistance
The World Health Organization has issued new guidelines for the treatment of chlamydia, gonorrhea, and syphilis in response to the growing threat of antibiotic resistance. According to the international health organization, each year, 131 million people are infected with chlamydia, 78 million are infected with gonorrhea, and 5.6 million are infected with syphilis.
-
The Growing Threat of Pyelonephritis Caused by Antibiotic-resistant Escherichia Coli
In patients with acute pyelonephritis due to Escherichia coli presenting to one of 10 emergency departments, fluoroquinolone resistance ranged from 6.3% to 19.9%.
-
Antibiotics, Breastfeeding, and the Intestinal Microbiota
Breastfeeding is associated with less frequent bacterial infections and with less subsequent obesity. Using antibiotics reduces or removes these favorable effects of breastfeeding, perhaps via alterations in the intestinal microbiota.
-
Guideline Update: Adults with Hospital-acquired and Ventilator-associated Pneumonia
The most notable new recommendation of the updated hospital-acquired pneumonia/ventilator-associated pneumonia guideline may be its endorsement of limiting the duration of antibiotic therapy to seven days in most cases.
-
Too Much of a Good Thing
In the United States in 2010 and 2011, an estimated 30% of outpatient oral antibiotic prescriptions may have been inappropriate, a finding that supports the need for establishing a goal for outpatient antibiotic stewardship.
-
Prolonged Empiric Antibiotic Therapy (PEAT) in Adult Intensive Care Units
Nine hundred ninety-eight patients admitted to 67 adult ICUs in 32 hospitals in the United States over a 24-hour period in 2011 were studied. Prolonged empiric antibiotic therapy was defined as continuing empiric antibiotics beyond 72 hours in patients in the absence of adjudicated infection as defined by CDC criteria. Three hundred thirty-three of 660 (50%) antibiotics were continued for at least 72 hours in patients who did not meet the CDC case definition of infection. Suspected pneumonia was the most common diagnosis in patients receiving PEAT. ICUs using invasive techniques to diagnose ventilator-associated pneumonia had lower rates of PEAT.
-
Longer Course Therapy for Lyme Disease Is Not Beneficial
A randomized, placebo-controlled clinical trial from the Netherlands found that longer-term antibiotic therapy for Lyme disease did not improve health-related quality of life compared to a standard course of treatment.
-
Antibiotic Use in Treatment of Children with Uncomplicated Severe Acute Malnutrition
Universal antibiotic use in the community-based treatment of uncomplicated severe acute malnutrition in children likely is not necessary in regions where suitable access to healthcare facilities is available.
-
Trimethoprim-sulfamethoxazole versus Placebo for Skin Abscesses After Incision and Drainage
A multicenter, double-blind, randomized clinical trial found that a 7-day course of trimethoprim-sulfamethoxazole following incision and drainage (I&D) resulted in a higher rate of cure for skin abscesses compared to I&D and placebo (80.5% vs 73.6%, respectively; P = 0.005).
-
The One and the Many: Experts Urge New Paradigm on Antibiotic Resistance
While the widespread overuse and misuse of antibiotics is frequently cited in discussions of increasing bacterial resistance, there are instances where even correct use for an individual patient raises the question of potential harm to others. A prevailing paradox in antibiotic therapy is that what is good for the one may be bad for the many.