Articles Tagged With: antimicrobial
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Preventing Clostridioides difficile Infections: Early De-escalation of Antipseudomonal Antibiotics
Early discontinuation of empirically administered antipseudomonal antibiotics may prevent many cases of Clostridioides difficile infection.
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Factors Associated With Urinary Tract Infections Caused by Multidrug-resistant Gram-negative Bacteria
A multicenter, retrospective, cohort study from southern and eastern Europe identified predictive factors for multidrug-resistant complicated urinary tract infections (cUTI), which included male sex, cUTI acquisition in a healthcare facility, presence of a Foley catheter, having a UTI in the previous year, and receiving an antibiotic in the preceding 30 days.
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Prophylactic Antibiotics for Acute Aspiration
Researchers compared outcomes in patients with aspiration pneumonitis who received prophylactic antibiotics during the first two days after macro-aspiration to patients who received only supportive care during this time. Among the 200 patients meeting the acute aspiration pneumonitis case definition, antimicrobial prophylaxis was not associated with improvement in mortality. However, patients receiving prophylactic antibiotics required more frequent escalation of antibiotics and received more days of antibiotics than those who were managed initially with supportive care alone.
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Inappropriate Outpatient Antibiotic Prescribing: The Need to Target Urgent Care Centers
Urgent care centers, which are part of a growth industry, are responsible for a large proportion of antibiotic prescriptions, including inappropriate prescriptions for acute respiratory diagnoses.
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Adverse Reactions to Antibiotics in Patients Receiving Outpatient Parenteral Antimicrobial Therapy
Approximately one-fifth of outpatient parenteral antimicrobial therapy recipients developed a clinically significant antimicrobial-related adverse drug event.
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Stewardship, Science, and Spirituality
Awareness of a patient’s and family’s belief system might help physicians appropriately frame explanations about the importance of antimicrobial stewardship.
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Emerging Infectious Disease and Emergency Medicine
There are many emerging infections for which the emergency physician must remain clinically vigilant. Although many infections may not represent true emergencies, it is important for ED providers to understand the epidemiology, presentation, and treatment of some of today’s common and life-threatening infections.
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How Many Personnel Are Required for Antimicrobial Stewardship? More Than You Have at Your Hospital
A work group in the Veterans Administration determined that the necessary staffing of antimicrobial stewardship programs dealing with inpatients (including long-term care) is 1.0 clinical pharmacy specialist with infectious disease knowledge and 0.25 physician (preferably trained in infectious disease) per 100 occupied beds. Needs for outpatient stewardship, which is now mandated, were not included in the assessment.
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Infectious Disease Alert Updates
Colistin Resistance in Action; PK-tailored High-dose Colistin May Not Be Beneficial; ‘Dragon’s Blood’ Yields Possible Antibacterial