Articles Tagged With: aspirin
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When and How to Stop Dual Antiplatelet Therapy After PCI
Among patients with high-risk percutaneous coronary intervention who had completed three months of dual antiplatelet therapy with ticagrelor, patients who were randomized to ticagrelor alone experienced similar ischemic outcomes and a lower risk of bleeding at one year compared with those maintained on ticagrelor and aspirin.
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Staged Preeclampsia Screening in Early Pregnancy
The use of 150 mg of daily aspirin from 11 to 14 weeks through 36 weeks of gestation reduces the rate of early preeclampsia (PE) in approximately 90% of at-risk pregnancies. In addition, aspirin also provides the benefit of reducing the risk of PE < 37 weeks by about 60% and the length of NICU stay by about 70%, primarily by reducing the number of neonates delivered before 32 weeks. What constitutes a high-risk patient and what quantifies patient-specific risks before PE develops remain to be answered.
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Low-Dose Aspirin and Preterm Birth
SYNOPSIS: A reanalysis of an earlier randomized clinical trial to assess the ability of low-dose aspirin to prevent preeclampsia has shown that the drug diminishes the risk of spontaneously delivering prior to 34 weeks by about half.
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Should Aspirin Be Used for Primary Prevention of Cardiovascular Events?
Primary prevention of cardiovascular disease and death by using daily low-dose aspirin is not recommended and should be reserved for those instances in which secondary prevention has been demonstrated to be effective in randomized clinical trials.
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Dual Antiplatelet Therapy for Acute Ischemic Stroke and TIA
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Dual Antiplatelet Therapy for Minor Ischemic Stroke or TIA
These investigators undertook this study to evaluate the effect of clopidogrel plus aspirin, vs. aspirin alone, in an international population of patients who had minor ischemic stroke or TIA — Platelet-Oriented Inhibition in New TIA and Minor Ischemic Stroke (POINT).
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Ticagrelor vs. Aspirin for Secondary Stroke Prevention — About the Same!
Ticagrelor was not found to be superior to aspirin in reducing the rate of stroke, myocardial infarction, or death within 90 days, but there was a trend toward a reduced rate of ischemic stroke, that did not reach statistical significance.
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Dual Antiplatelet Therapy Appears More Effective Than Single Therapy
How long should duel antiplatelet therapy after stroke or transient ischemic attack last?
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Optimal Antiplatelet Therapy for Secondary Prevention of Ischemic Stroke
This study strongly suggests that compared with maintaining patients on aspirin alone, switching to a different antiplatelet agent, or adding a second antiplatelet agent to aspirin may be better in preventing subsequent vascular events in patients who experienced a new ischemic stroke while taking aspirin.
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Low-dose Aspirin and Preeclampsia
A study comparing outcomes before and after offering low-dose aspirin to patients who were deemed to be high risk by a first trimester protocol showed a decrease in preterm birth prior to 34 weeks and a decrease in early-onset preeclampsia.