Articles Tagged With: bacteremia
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Cefazolin and Ertapenem as Salvage Therapy in Methicillin-Susceptible Staphylococcus aureus Bacteremia
Cefazolin (CZ) and ertapenem combination therapy was successfully used to salvage 11 cases of persistent methicillin-susceptible Staphylococcus aureus bacteremia. Modest in vitro synergy between CZ and ertapenem was demonstrated on testing of six clinical isolates, but in vivo activity appeared more potent in an animal model than as predicted by in vitro activity.
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What Is the Risk of Joint Prosthesis Infection Resulting From Bacteremia?
The risk of periprosthetic joint infection resulting from bacteremia depends on the organism.
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Preventing Readmissions and Optimizing Outcomes for Staphylococcus aureus Bacteremia: Still a Long Journey Ahead
Using a population-based database, investigators found that the rate of readmission within 30 days following hospitalization for S. aureus bacteremia was high (22%) and resulted in high cost to the healthcare system.
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Fatal Bacteremia Due to Fecal Microbiota Transplantation
Two patients developed bacteremia due to an extended-spectrum beta-lactamase producing Escherichia coli that had been transmitted to them via stool transplantation.
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Combination Therapy With Daptomycin Plus Beta-Lactam Antibiotics in MSSA Bacteremia
In a retrospective cohort study of 350 patients, the combination of a beta-lactam antibiotic plus daptomycin was not superior to beta-lactam monotherapy in patients with bacteremia due to methicillin-susceptible Staphylococcus aureus.
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Staphylococcus aureus Bacteriuria: What Is the Significance?
In a retrospective study from Canada, researchers reported several risk factors for serious Staphylococcus aureus infections, including bacteremia and vertebral osteomyelitis, in patients with S. aureus bacteriuria.
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IV to Oral Conversion of Antibiotic Therapy for Bacteremia Due to Enterobacteriaceae
Oral step-down antibiotic therapy (IV to oral conversion) is safe and effective in patients with bloodstream infection due to Enterobacteriaceae.
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Duration of Intravenous Antibiotic Therapy for Late-Onset Neonatal Group B Streptococcal Bacteremia
Although standard treatment of late-onset neonatal group B Streptococcus bacteremia includes intravenous antibiotic therapy for 10 days, shorter courses seem safe and effective.
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Treatment of Gram-Negative Bacteremia: How Long Is Long Enough?
Antibiotic administration for seven days is sufficient in stable patients with Gram-negative bacteremia.
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Probiotics for the Primary Prevention of Clostridium difficile Infection
The authors of a before-and-after intervention study and a meta-analysis found that probiotics reduce the incidence of Clostridium difficile infection (CDI). The strategy seems to work best in hospital settings where the incidence of CDI is ≥ 5% and for patients receiving two or more antibiotics.