Articles Tagged With:
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Stigmatizing Language Can Lead to Diagnostic Errors, Patient Harm
Stigmatizing language is inappropriate in healthcare and can easily seep into documentation and verbal communication. One of the worst effects of such comments is that it can lead to diagnostic errors and other threats to patient safety, according to recent research.
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Safety II Framework Aims to Improve Safety, Eliminate Useless Tasks
A better approach to patient safety can eliminate much of the useless and redundant tasks that burden clinicians and do little to avoid harm, says a researcher who encourages risk managers to consider the natural tendencies of people in the workplace.
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CMS Moving to Address Patient Harm with Additional Measures
Centers for Medicare & Medicaid Services is planning to introduce additional requirements to improve patient safety, and risk managers would be wise to anticipate how those new measures might affect their operations.
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New Noncompete Rule Requires Reevaluation of Healthcare Agreements
A recent decision by the Federal Trade Commission changes how healthcare organizations can limit the activities of employees after they resign or are terminated, requiring a review of any noncompete agreements currently in place and policies that require them..
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Results from GLP-1 Receptor Agonists in Early Parkinson’s Disease
This paper demonstrated that after one year of treatment, lixisenatide resulted in less progression of motor disability. Longer studies are needed to determine if this represents true disease modification.
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Brentuximab Neuropathy
Brentuximab, an antibody-drug conjugate for the treatment of lymphomas, carries a high risk of inflammatory sensory and motor neuropathies.
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Risk of Autism After Prenatal Topiramate, Valproate, or Lamotrigine Exposure
The incidence of autism spectrum disorder was higher among children with prenatal exposure to the topiramate, valproate, and lamotrigine than the risk in the general population. However, after adjustment for indication of the medication (epilepsy) and other confounders, an increased risk was only observed in children with prenatal exposure to valproate.
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Seizures in Adolescents: Motor or Nonmotor?
The rate at which motor vs. nonmotor seizures are recognized in adolescents is unknown. This retrospective analysis demonstrates a high rate of misrecognition of nonmotor seizures among adolescents presenting to an emergency department and frequent misrecognition of any nonmotor seizures in those presenting with a first-time motor seizure.
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Novel Gene Therapy for Giant Axonal Neuropathy
The authors conducted a Phase I trial of a gene editing approach delivered by adeno-associated virus vector carrying a codon-optimized human giant axonal neuropathy transgene. The transgene targets anterior horn motor neuron bodies and sensory neurons in the dorsal root ganglia with the goal of repairing peripheral nerves and their axons. Each patient received a single intrathecal injection of the investigational agent. At one year, patients had less progression of disease compared to pretreatment intervals.
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Ceftobiprole Medocaril Sodium for Injection (Zevtera)
The U.S. Food and Drug Administration has approved a new cephalosporin antibacterial for the treatment of three serious infections: bloodstream, skin and skin structure, and community-acquired pneumonia. Ceftobiprole is a fifth-generation cephalosporin with in vitro activity against gram-positive and gram-negative bacteria including multidrug resistant organisms. It will be distributed by Basilea Pharmaceutica International Ltd, Allschwil as Zevtera.