Hospitalized COVID-19 patients with cognitive complaints demonstrate reduced attention and executive dysfunction on formal cognitive testing consistent with the same frequency and pattern of cognitive changes associated with critical illness.
Individuals with Parkinson’s disease dementia and orthostatic hypotension (OH) showed more robust cognitive improvement from rivastigmine vs. those without OH. The anti-OH effect of rivastigmine probably mediates this better response.
SYNOPSIS: In this large prospective cohort study of subjects in Manhattan, researchers demonstrated an association between exposure to air pollution and decline in cognitive function over time in one cohort, but not the other.
Clinical identification of fluctuating cognition is challenging. A better understanding of potential etiological mechanisms can allow for optimization of clinical assessment tools and targeted therapeutic approaches.
The authors of a recent study evaluated the effect of discontinuing cannabis use in patients with multiple sclerosis. Stopping cannabis led to significant improvements in memory, processing speed, and executive function.