Articles Tagged With: hemoglobin
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Understanding the Utility of Hemoglobin A1c in Diagnosing Gestational Diabetes in Early Pregnancy
In this retrospective cohort study of 243 pregnant women who had combined hemoglobin A1c (HbA1c) and a two-step oral glucose tolerance testing at less than 21 weeks of gestation, median values of HbA1c were higher in women with gestational diabetes compared to nondiabetics (5.8% compared to 5.3%; P < 0.001). The predictive probability of using HbA1c in diagnosing diabetes in early pregnancy was high compared to two-step testing (area under the curve, 0.8), with an optimal diagnostic threshold of 5.6%. Although a HbA1c level of > 6.5% is diagnostic of early gestational diabetes, a lower diagnostic threshold might be justified during pregnancy.
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Sickle Cell Emergencies
This article provides an overview of the most frequently encountered complications associated with sickle cell disease seen in the emergency department. It will discuss recent guidelines and novel approaches to the treatment of entities such as acute chest syndrome, vaso-occlusive crisis, and stroke, as well as new treatments on the horizon.
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Pediatric Hematologic Emergencies
MONOGRAPH: In-depth disorders of the hemogram: red blood cells, platelets, and white blood cells.