Transplacental antibodies against Plasmodium falciparum Schizont Egress Antigen-1 may protect infants from severe malarial infection during the first year of life. This new knowledge about these antibodies potentially can inform vaccine development.
New guideline recommendations indicate that the only unequivocal indications for screening and treatment of asymptomatic bacteriuria are pregnancy and undergoing endoscopic urologic procedures associated with mucosal injury.
Infants with severe bronchiolitis sometimes develop subsequent recurrent wheeze and asthma. Among infants hospitalized with bronchiolitis, the risk of developing asthma is greatest in those with rhinovirus C infection, especially if they also are sensitized with IgE against foods.
In a randomized, controlled trial of adult patients with bone or joint infections, researchers found oral antibiotic therapy was noninferior to intravenous therapy based on treatment failure at one year.