It Is Uncertain if Men and Women Present with Different Symptoms at the Onset of Ischemic Stroke

There have been anecdotal reports and small case series that have suggested women may present with symptoms that are different from men at the onset of ischemic stroke or transient ischemic attacks. These investigators conducted a systematic review to determine if there was a difference in presenting symptoms between men and women.

Men Are More Likely to Have High-Risk and Dangerous Carotid Artery Plaques than Women

Investigators in the Netherlands investigated the differences between atherosclerotic plaque burden and plaque morphology between men and women who had recent ischemic stroke symptoms and less than 70% ipsilateral carotid artery stenosis.

Hypertensive Disorders of Pregnancy Are Associated with an Increased Risk of Ischemic and Hemorrhagic Stroke

It has been established that women who have hypertension during pregnancy from any cause, compared to those without a history of hypertension, have an increased risk for subsequent stroke. Investigators in this study from Taiwan looked at the differences between the four major types of hypertensive disorders and the relative risks of subsequent stroke in women.

In Young Adults, Marijuana Use Is Not Associated with Increased Risk of Early Onset Ischemic Stroke

Marijuana use, both recreational and medical, is increasing among young adults, and many states are legalizing its use. A variety of cardiovascular effects have been described, which could increase the risk of cardiovascular complications, including stroke, and some observational studies have suggested an increased stroke risk from marijuana use. But there are few epidemiological studies that have evaluated this association.

Basilar Artery Occlusion: Endovascular Thrombectomy and Medical Therapy Have Similar Outcomes

Basilar artery occlusion is a rare form of ischemic stroke and accounts for about 10% of large vessel occlusions reported in the literature. These investigators conducted a randomized trial, enrolling patients from 2011 through 2019, even though multiple studies published in 2015 demonstrated benefit of endovascular therapy in anterior circulation large vessel occlusions. Efficacy and safety were compared with medical therapy in patients who underwent endovascular therapy within six hours after the estimated time of onset of symptoms.

Intracranial Plaque Rupture and Stroke

An MRI study of cerebral circulation in patients with embolic stroke of undetermined etiology showed evidence of atherosclerotic plaque in most patients.

Plant-Based Diet Could Cut Stroke Risk

Eating a diet rich in beans, vegetables, and whole grains was beneficial in a long-term study.

Recurrent Stroke After Embolic Stroke of Undetermined Source

Twenty percent to 40% of ischemic strokes are classified as cryptogenic, meaning a specific cause cannot be identified. A subset of those have been classified by some investigators as embolic stroke of undetermined source. However, this remains a controversial category and classification.

Ticagrelor Added to Aspirin Reduces Long-Term Risk of Recurrent Stroke or Death After Ischemic Stroke or TIAs

The Acute Stroke or Transient Ischemic Attack Treated with Ticagrelor and ASA for Prevention of Stroke and Death (THALES) study was designed to test the hypothesis that 30-day treatment with ticagrelor and aspirin would be superior to aspirin alone in reducing the risk of subsequent stroke or death in patients who had a non-cardioembolic ischemic stroke or transient ischemic attack.

COVID-19 Infection Increases Stroke Risk by Almost Eight Times the Stroke Risk with Influenza

It is well documented that influenza epidemics are associated with an increased risk of ischemic stroke and myocardial infarction, as are all systemic inflammatory disorders. Investigators at Weill Cornell Medicine wanted to determine if coronavirus infection induced a higher risk of ischemic stroke than other viral infections, such as influenza.

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