Articles Tagged With: preterm
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Does Treatment of Bacterial Vaginosis Prevent Spontaneous Preterm Birth?
In this randomized, controlled trial from France, screening for and treatment of bacterial vaginosis in pregnant women at low risk for preterm birth with oral clindamycin or placebo did not reduce the rate of spontaneous preterm birth between 16 and 36 weeks.
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Blood Test for Pregnant Women May Predict Preterm Births
In pilot studies of pregnant women, data indicate that ribonucleic acid-based tests of maternal blood can predict delivery date and risk of early childbirth.
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Fetal Fibronectin: Its Role in Threatened Preterm Labor
A recent letter to the editor disputes the conclusion of an earlier study that fetal fibronectin is of little value in threatened preterm labor, despite other studies suggesting that when used in conjunction with cervical length measurements, it can diminish unnecessary hospitalizations appreciably.
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Antenatal Steroids for Very Early PTB
A large European multicenter study has shown that antenatal corticosteroid administration in patients at risk for imminent very early preterm birth (24 to 31 weeks) will decrease perinatal mortality and morbidity substantially, even after only three hours of exposure.
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17 P vs. Vaginal Progesterone
A recent randomized study suggested that vaginal progesterone is at least as good as, and may be superior to, intramuscular 17 alpha-hydroxy progesterone caproate in preventing recurrent preterm birth, but shortcomings in the study indicate that more investigation is needed.
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Preterm Premature Rupture of Membranes: When to Deliver?
A recent large multicenter, randomized clinical trial has shown that delivering patients with premature preterm rupture of membranes at 34 weeks, rather than pursuing a watchful waiting approach until 37 weeks, does not afford greater protection against neonatal sepsis.
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Does a History of D&C Increase the Risk of Premature Delivery?
In a meta-analysis, a history of dilation and curettage for management of miscarriage or termination of pregnancy was associated with an increased risk of preterm birth in a subsequent pregnancy but the association is weak and most likely explained by confounding.
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Neonatal MRI Can Predict Future Academic Difficulties for Children Born Preterm
Neonatal brain MRI can identify structural changes that predict future difficulties in school performance for children who are born preterm.
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Progesterone and Indomethacin and PTL
One recent study has questioned the efficacy of the ability of 17 alpha-hydroxyprogesterone caproate to prevent preterm birth, and the other suggests that indomethacin, used to stop preterm labor, may have unwanted neonatal consequences.
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Delayed Cord Clamping
Although a recent study has failed to show major benefit from delayed umbilical cord clamping, others have suggested neonates having delayed cord clamping have less need for transfusion, higher hematocrits, less neonatal morbidity, and diminished risk of intraventricular hemorrhage.