Articles Tagged With: prophylaxis
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Tafenoquine for Malaria Prevention and Relapse Treatment
Tafenoquine is effective for the prevention of all species of malaria and can be used to prevent relapse of Plasmodium vivax and Plasmodium ovale. G6PD status should be evaluated prior to use.
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Routine Drug Prophylaxis in Dentistry Usually Unnecessary, May Cause Patient Harm
With antibiotic stewardship now required in hospitals and increasingly normalized in other healthcare settings, dental offices are something out of an outlier.
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Infectious Disease Alert Updates
Multi-Modal Interventions for Controlling CRE: Which Is Best? Antimicrobial Resistance Genes — in the Arctic; Updated PEP Guidelines for Hepatitis A Vaccine
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A Rabies Death in Virginia
A Virginia resident who had not received pre- or post-exposure prophylaxis died of rabies resulting from a dog bite during a prolonged trip to India. Many exposed healthcare workers subsequently received post-exposure prophylaxis.
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In Patients Who Self-catheterize, Antibiotic Prophylaxis Prevents UTIs but Increases Antibiotic Resistance
A randomized, open-label, superiority trial found that daily antibiotic prophylaxis for patients who use clean, intermittent self-catheterization reduced symptomatic urinary tract infections by 48% over a 12-month period. Antibiotic resistance became prevalent in urinary isolates from the group receiving prophylaxis compared to controls.
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Pneumococcus, Sickle Cell Disease, Vaccination, and Penicillin
Even in the era of newborn screening, pneumococcal vaccination, and penicillin prophylaxis, children with sickle cell disease continue to be at risk of morbidity and mortality from invasive pneumococcal disease, mostly from non-vaccine serotypes.
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Letermovir Prophylaxis Is Effective in Preventing Cytomegalovirus Infection After Hematopoietic Stem Cell Transplantation
A Phase III, randomized, double-blind, placebo-controlled superiority trial that included patients 18 years of age or older undergoing allogeneic hematopoietic stem cell transplantation found that prophylaxis with letermovir resulted in significantly lower risk for cytomegalovirus infection in the first 24 weeks than placebo. Safety and adverse events were similar between letermovir and placebo.
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HIV Pre-exposure Prophylaxis for Adolescents: A Health Equity and Reproductive Justice Issue
Access to HIV pre-exposure prophylaxis is not just a public health issue, but equally important, an equity and justice issue.
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Adding Azithromycin to Standard Prophylaxis in Non-Elective Cesarean Sections?
Adding intravenous azithromycin to “routine” cephalosporin prophylaxis prior to non-elective cesarean section delivery significantly reduces the risk of postpartum endometritis and wound infection.
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Diagnosis and Management of Invasive Aspergillosis in 2016
This updated guideline takes into account newer diagnostic methods and therapeutic agents and their use in the treatment of aspergillosis.