Bridging therapy with intravenous thrombolysis appears to be associated with improved functional outcome without any additional complications compared to direct mechanical thrombectomy for patients with acute ischemic stroke who have LVOs.
Message from the editor: The following reviews of studies presented at the 2018 International Stroke Conference were written after my personal attendance at the presentations, followed by review of the simultaneous publications in the journals Stroke, The New England Journal of Medicine, JAMA Neurology, and the Journal of the American Medical Association.
Acute stroke reperfusion therapies have led to significant reduction in the morbidity and mortality associated with ischemic strokes due to large vessel occlusion. This article will discuss the prevalence, mechanism, diagnosis, and treatment options of acute ischemic stroke due to large vessel occlusion.
Among a group of ischemic stroke patients last known to be well six to 24 hours earlier and who had a mismatch between clinical deficit and infarct size, outcomes regarding disability and functional independence were better if treated with mechanical thrombectomy, rather than standard care alone.
this meta-analysis of thrombectomy in patients with large vessel ischemic stroke demonstrated that earlier treatment compared with medical therapy alone was associated with lower degrees of disability at three months.