OB/GYN Clinical Alert – February 1, 2020
February 1, 2020
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What Are the Roles of the Combined Oral Contraceptive Pill and Metformin in the Management of Polycystic Ovary Syndrome?
This systematic review documents the effectiveness of combined oral contraceptive pills in treating hyperandrogenism and irregular menses, and of metformin in addressing the metabolic disturbances in women with polycystic ovary syndrome.
In this randomized controlled trial, there was no difference in pain score with tenaculum placement between the slow method of application and coughing with application (median pain score 44 vs. 32, P = 0.16).
Longer lifetime exposure to endogenous estrogen and menopausal estrogen replacement were associated with better cognitive status in older adult women. Women who initiated estrogen therapy early (within five years of the onset of menopause) showed higher cognitive test scores than those who started later.
Low libido is the most common sexual complaint, affecting up to 38.7% of women, with up to 12.3% also reporting significant distress associated with this condition. In the past five years, for the first time in history, there are two Food and Drug Administration-approved medications specifically for treating hypoactive sexual desire disorder in women. Of note, both medications are central nervous system agents.