Bacterial Infections
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Empiric Anti-MRSA Therapy in Pneumonia May Not Always Be a Good Idea
In a retrospective cohort study, empiric anti-methicillin-resistant Staphylococcus aureus treatment was not associated with a reduction in mortality in any subgroup of patients studied and appeared to cause harm in many.
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Clindamycin Improves Outcomes in Necrotizing Fasciitis Due to Group A Streptococcus
Using a murine model of necrotizing fasciitis, investigators determined that clindamycin inhibits key virulence factors of Group A Streptococcus, and should be given as soon as possible and at high doses to reach levels above MIC in affected tissues.
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Vitamin D to Prevent Acute Respiratory Infections?
Vitamin D supplementation is associated with a decreased risk of respiratory infections, especially in those who had low circulating levels of 25-hydroxyvitamin D.
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If they’re so difficult to reprocess, why are duodenoscopes approved for surgery?
With all of the difficulties in cleaning duodenoscopes, and the potential for outbreaks of carbapenem-resistant Enterobacteriaceae, some outpatient surgery managers are questioning why these scopes are approved by the Food and Drug Administration. However, the benefits outweigh the risks, some sources say.
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Culturing protocols devised for duodenoscopes to prevent CRE
Responding to a series of outbreaks of carbapenem-resistant Enterobacteriaceae (CRE) linked to duodenoscopes, the Centers for Disease Control and Prevention has developed an interim protocol for culturing the devices before use to create a greater margin of safety for patients. But as others have noted, the approach is not foolproof and could be costly if facilities determine that they must purchase more scopes to adopt the protocol.
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Abstract & Commentary: Pertussis in Infants in California
A total of 32 infants younger than age 3 months with pertussis hospitalized at a large childrens hospital in Southern California were compared to 92 control patients hospitalized with RSV or influenza virus infections. -
Case Report: Seaweed Poultices and Vibrio Infection
This report details the occurrence of an infected, cellulitic lower extremity wound infection in a 70-year-old British woman secondary to an unusual Vibrio species, V. alginolyticus. -
Abstract & Commentary: New Malaria Recommendations for Greece — October, 2011
Greek health authorities recently published findings of 36 cases of Plasmodium vivax malaria in Greece occurring between May 2011 and September 2011. -
Abstract & Commentary: Streptococcus bovis Group Organisms and the Association with Colon Cancer: Pinning the Tail on the Donkey
The association between S. bovis group infection (particularly endocarditis) and concurrent colorectal neoplasia has been known for some time. -
Clinical Briefs in Primary Care supplement