Clinical Publication
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Adjuvant Systemic Corticosteroid Therapy in Hospitalized Patients with Community-Acquired Pneumonia
In this meta-analysis, all-cause mortality, ICU admission, and incidence of adverse events were similar in patients who received corticosteroids compared to standard care. However, the corticosteroid therapy group recorded a lower incidence of progression to mechanical ventilation.
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Fezolinetant Tablets (Veozah)
Fezolinetant can be prescribed to treat moderate-to-severe vasomotor symptoms caused by menopause.
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Momentum Continues for Transcatheter Edge-to-Edge Repair
A flurry of recently released study data provided more evidence supporting the efficacy of the minimally invasive heart procedure.
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A Hidden Rhythm
The only clinical information available for this tracing is that the ECG was obtained from an older woman. Without any other background, where should we go from here?
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Cardiovascular Outcomes with Bempedoic Acid, a New Statin Alternative
A trial of bempedoic acid vs. placebo for statin-intolerant patients showed bempedoic acid significantly lowered LDL cholesterol levels and prevented more major adverse cardiovascular events after a median follow-up of 41 months. Although nonserious side effects were numerically higher for those on bempedoic acid, serious adverse events were not significantly different from placebo.
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Sitting, Standing, and Walking: The Effect on Cardiometabolic Markers
The authors of this meta-analysis explored the effects of interrupting sitting with either light-intensity walking or standing. They found light-intensity walking was associated with the most significant effect on several markers of cardiometabolic health.
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The Effects of Video Feedback on Parenting Children with Behavioral Problems
This randomized trial of an in-home parenting intervention consisting of review of video interactions and feedback promoting positive parenting was associated with fewer behavioral problems in high-risk children (ages 1 to 3 years) compared with usual care.
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Focused Ultrasound Ablation of the Subthalamic Nucleus for Parkinson’s Disease Tremor
Researchers demonstrated the long-term efficacy and safety of unilateral MRI-guided high-frequency ultrasound subthalamotomy for Parkinson’s disease patients with motor fluctuations and dyskinesia three years after the procedure.
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Patients Managing Severe Hypertension Should Avoid Drinking Too Much Coffee
Among patients with severe hypertension, drinking two or more cups of coffee a day was associated with twice the risk of death from cardiovascular disease, while green tea did not increase risk.
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Respiratory Syncytial Virus Vaccine, Adjuvanted (Arexvy)
Arexvy can be administered to prevent lower respiratory tract disease caused by respiratory syncytial virus in patients age 60 years and older.