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This multicenter randomized trialnicknamed the VISEP studyused a two-by-two factorial design to test two independent treatments in severe sepsis patients.
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Most of the attention on catheter-related bloodstream infections (CR-BSI) in the ICU focuses on central venous catheters (CVC), a bias that likely derives, in part, from the 2002 Centers for Disease Control guidelines which stipulate that arterial catheters (AC) have "low infection ratesrarely associated with bloodstream infections.
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A prospective observational study was conducted to assess diagnostic and therapeutic efficacies of a daily routine CXR and to evaluate the impact of discontinuing this practice. The setting was a 10-bed mixed medical-surgical ICU of a non-academic teaching hospital in The Netherlands.
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n this issue: Stop smoking drug Chantix rates stronger warning from FDA; Type 2 diabetes surgery on the way?; Vytorin study inconclusive; Influenza A virus found resistant to Tamiflu; FDA actions.
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Most critically ill patients require mechanical ventilation, and, according to one large survey, the weaning process occupies about 40% of the time that patients spend connected to the ventilator.
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Prilosec and Nexium Cleared; Anastrozole over Tamoxifen for Breast Cancer; Antibiotics and Steroids Not for Sinusitis; FDA Actions
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In the majority of patients who develop the acute respiratory distress syndrome (ARDS), oxygenation can be supported using increased inspired oxygen concentrations (FIO2) or higher levels of positive end-expiratory pressure (PEEP).
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Invasive aspergillosis (IA) is increasingly recognized as a source of infection in immunocompromised ICU patients, but accurate diagnosis remains challenging.