Infectious Disease
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Infectious Disease Updates
Is Your Hospital Bed Contaminated? The Surgical Skin Prep Debate Thickens
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Outpatient CAP Treatment in Adults: Narrower Spectrum Therapy Is Better Tolerated
Examination of a large database led to the conclusion that treatment of community-acquired pneumonia in outpatients with narrower-spectrum agents (macrolides or doxycycline) was associated with similar clinical outcomes but with a lower incidence of adverse effects when compared to broader-spectrum therapy.
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Parasites and Poverty in the South
Parasite contamination of soil remains prevalent in some areas of the southern United States.
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Aztreonam-Avibactam vs. Meropenem for Serious Gram-Negative Bacterial Infections
In this multinational, prospective, Phase III, randomized trial, aztreonam-avibactam was found to be a safe and effective option, when compared to meropenem with or without colistin, for treating complicated intra-abdominal infections, hospital-acquired pneumonia, and ventilator-acquired pneumonia caused by gram-negative bacteria.
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Effectiveness of Nirmatrelvir-Ritonavir in Hospitalized Patients with COVID-19
A study that compared nirmatrelvir-ritonavir, remdesivir, or a combination of both for hospitalized patients with COVID-19 found those who received nirmatrelvir-ritonavir monotherapy had lower mortality, reduced intensive care unit admission, and reduced need for mechanical ventilation.
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Pink Eye: Do Antibiotics Matter?
Acute infectious conjunctivitis, commonly referred to as pink eye, is common in children and is caused by bacteria more often than by viruses. Nonetheless, neither the clinical course of uncomplicated cases nor the spread of infection to peers is significantly altered by treatment with topical antibiotics or by exclusion of infected children from daycare and school settings.
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Doxy-PEP Could Be Prevention Strategy for Some Patients
Post-exposure prophylaxis (PEP) of doxycycline is recommended by the Centers for Disease Control and Prevention (CDC) for prevention of chlamydia, syphilis, and gonorrhea infections for men who have sex with men (MSM) and transgender women who have had a bacterial sexually transmitted infection (STI) within the past year, according to a new paper on doxycycline-PEP. But it also is a strategy that may work well for cisgender women who have a similar risk profile.
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Routine, Opt-Out Screening for Syphilis in Emergency Departments Succeeds
The current healthcare crisis of increases in cases of congenital syphilis suggest reproductive health providers and the public health community need better strategies for identifying people with syphilis infection and getting them into treatment.
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A Review of Throat Infections: Low-Acuity Disease
Sore throats are common pediatric chief complaints, with etiologies ranging from thrush to epiglottitis. All clinicians must be familiar with the diversity of causes from benign to life-threatening in order to decrease morbidity and mortality with a timely diagnosis.
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Infectious Disease Updates
ID: An Arbiter of Death? Preventing Recurrent UTI with Probiotics