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Overall, caspofungin was at least as effective as liposomal amphotericin B for empiric therapy in persistently febrile neutropenic patients. Caspofungin therapy was associated with greater survival 7 days after the end of therapy, greater efficacy in treatment of baseline fungal infections, and it was better tolerated.
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Cockerill and colleagues examined the effects of the volume of blood, the number of consecutive blood culture specimens, and the incubation time on the recovery of pathogens from 37,568 blood cultures obtained from adults. The study was performed at the Rochester, MN Mayo Clinic from 1996 to 1997, and used the automated BACTEC 9240 instrument.
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Bed Bugs Are Back; Can You Guess the Pathogen?; If It Was a Bear, It Would Have; More Bites.
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Bacteriologic and clinical failures in adults with Streptococcal tonsillopharyngitis are twice as likely with oral penicillin therapy as with cephalosporin treatment. But, what is the significance of this finding?
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Synopsis: Shortly after patronizing a restaurant, 117 individuals developed an illness characterized by fever, myalgia, chills, and headache. Respiratory symptoms were present in fewer than half. Legionella anisa was found to be the cause of this outbreak of Pontiac fever.
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Synopsis: Volatile organic compounds from fecal samples appear to have good sensitivity and specificity for many enteric pathogens and could lead to rapid diagnostic testing.
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The following summary of selected abstracts from 3 meetings will be published in multiple parts. The 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) met in Chicago September 14-17, 2003. The Infectious Disease Society of America (IDSA) met in San Diego October 9-12, 2003. The American Society of Tropical Medicine and Hygiene met in Philadelphia December 3-7, 2003.
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The World Bank is funding a novel project to train 30 giant pouched rats to sniff out tuberculosis (TB) in respiratory specimens in Sub-Saharan Africa.
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Hypothyroidism and Pregnancy; Anti-Depressants and the Risk of Suicide; FDA Actions; Brief Notes.