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A topical estradiol emulsion has been approved for treating symptoms of menopause. Currently available estrogen products include pills, patches, and vaginal rings. The new estrogen emulsion provides another option for estrogen therapy. Novavax Inc markets this topical formulation as Estrasorb.
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Oral rofecoxib (Vioxx) may have a role in controlling postoperative pain patients undergoing knee surgery.
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The first head-to-head comparison study of an ACE inhibitor and an angiotensin receptor blocker, to assess renoprotective effects in type 2 diabetes, has shown that the drugs are comparable in their benefit.
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The consecutive rhythm strips seen in the Figure were obtained from a 73-year-old man with a history of ischemic cardiomyopathy. QRS widening is the result of underlying bundle branch block. In view of the atrial activity seen in these rhythm strips, what would you want to ask the patient?
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In an attempt to clarify the role of early intensive glycemic control, newly diagnosed type 2 diabetes patients were treated with insulin by means of an insulin pump on an inpatient basis for two weeks, after which they were discharged.
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A new non-aluminum, non-calcium, phosphate binder has been approved by the FDA.
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Over a 7-year period, there was a dramatic increase in the isolation of community-acquired MRSA in the San Francisco area. Molecular typing showed movement of community-acquired strains into hospitals.
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A new randomized trial using either a calcium channel blocker or an ACE inhibitor to lower systolic blood pressure to the low 120s prevented cardiac events in patients with coronary artery disease compared with systolic blood pressures around 130.
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Sleep restriction (to 4 hours a night) resulted in increased appetite, increased cortisol levels, lowered TSH levels, worsened glucose tolerance and lower heart rate variability compared with sleep extension (to 12 hours a night) in young healthy volunteers.
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Measures that increase adiponectin levels might be valuable targets for decreasing the risk of atherosclerosis present in patients with diabetes.
