Obstetrics/Gynecology General
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Cesarean Scar Ectopic Pregnancy
Cesarean scar ectopic pregnancy is a complication in which an embryonic pregnancy implants in the fibrous scar of a previous cesarean incision. This abnormally located pregnancy places the patient at increased risk for uterine dehiscence, hemorrhage, and abnormal placentation as the pregnancy progresses.
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How Common Are Hormonal Side Effects with the 52-mg Levonorgestrel IUD?
In this secondary analysis of the ACCESS IUS trial, participants who used combined hormonal contraceptives compared to nonhormonal contraceptives prior to enrolling were more likely to complain of acne in the first six months (13% vs. 8.5%, P = 0.006) and 12 months (15.7% vs. 10.6%, P = 0.005) of levonorgestrel intrauterine device use. Overall, the rate of discontinuation in the first six months because of adverse events was 5.5%, with no difference between the two groups.
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Regret in Younger Patients After Minimally Invasive Hysterectomy
A matched retrospective cohort study including 77 participants younger than 30 years of age and 164 participants aged 31-49 years demonstrated that a younger participant cohort had significantly higher rates of surgical and loss-of-fertility regret compared with an older participant cohort (32.5% vs. 9.1%, P < 0.001 and 39.0% vs. 13.4%, P < 0.001, respectively).
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Preterm Birth and the RSV Vaccine During Pregnancy
The follow-up MATISSE study explored the safety of the respiratory syncytial virus prefusion F (RSVpreF) vaccine in pregnant women and demonstrated no significant increase in preterm birth rates compared to the placebo, although it highlighted geographical and socioeconomic disparities in outcomes.
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Self-Testing for STIs Can Help Improve Access and Reduce Outbreaks
The increasing cases of syphilis, congenital syphilis, and some other sexually transmitted infections (STIs) in the post-pandemic era suggest clinicians and public health departments need additional strategies and tools to combat the problem.
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Vaccine Hesitancy Could Dampen Enthusiasm for Vaccines to Combat STIs
While the sexually transmitted infection (STI) prevention world’s research pipeline contains new vaccines to fight major STIs — a potentially exciting development — there also is concern about growing vaccine hesitancy and misinformation in the United States.
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Abortion Training Increasingly Affected by Dobbs Decision
OB/GYN abortion training programs have been negatively affected by logistical and financial burdens in the nearly three years since the U.S. Supreme Court overturned Roe v. Wade and universal abortion access rights with its decision in Dobbs v. Jackson Women’s Health Organization on June 24, 2022.
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Contraceptives Can Be Used to Prevent Cancer, Help with Multiple Medical Conditions
Contraceptives can help patients who are experiencing other conditions, including menstrual pain, endometriosis, heavy menstrual bleeding, menopause, and disabilities.
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Parvovirus and Increasing Danger in Pregnancy and Sickle Cell Disease
The incidence of human parvovirus B19 infection is increasing in the United States, putting vulnerable groups at risk of serious complications.
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Intrauterine Instillation of Mepivacaine at the Time of IUD Placement
In a randomized clinical trial of 151 women, intrauterine instillation of mepivacaine significantly reduced pain with intrauterine device insertion on visual analog scales both before (53.9 mm vs. 67.2 mm, respectively; P < 0.001) and after adjustment for individual provider variability (55.2 mm vs. 77.4 mm, respectively; P < 0.001), compared to placebo.