Pain
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Pain Researchers Are Engaging Patients as Partners
Pain researchers would benefit by enacting a comprehensive approach to patient engagement, perhaps engaging people with lived experience of chronic pain in developing study recruitment materials.
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Do Anti-Inflammatory Drugs Cause More Chronic Pain?
Acute inflammation may protect against the development of chronic pain through neutrophil activation. Using nonsteroidal anti-inflammatory drugs may blunt that response and contribute to chronic pain.
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Atogepant Tablets (Qulipta)
Atogepant can be prescribed to prevent episodic migraine in adults.
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Prednisone vs. Placebo in Short-Term Prevention of Episodic Cluster Headaches
Prednisone, given at 100 mg for five days and then tapering by 20 mg every three days, is a safe and effective short-term prevention for episodic cluster headaches while waiting for longer-acting preventive agents to be initiated.
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Oral Calcitonin Gene-Related Peptide Antagonist for Migraine Prevention
Atogepant, an oral calcitonin gene-related peptide antagonist, was shown to be effective and safe for migraine prevention.
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Oliceridine Injection (Olinvyk)
Oliceridine should be prescribed to adults to manage acute pain severe enough to require intravenous opioid analgesic and for whom alternative treatment has not worked.
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Are Epidural Steroid Injections Cost-Effective?
In a retrospective review of patients treated for low back pain and lumbar radiculopathy at the Cleveland Clinic, at three- and six-month follow-up, epidural steroid injections were no better than conservative therapies in quality of life measures or overall cost of medical care.
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Prognosis in Small Fiber Neuropathy
Small fiber neuropathy is a common disorder that causes chronic pain, but rarely progresses to disability or more severe neurological disorders. Management of the pain continues to be the major challenge in treatment.
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Risk of Neuropathy With Fluoroquinolones
As a class, fluoroquinolones are some of the most commonly used antibiotics worldwide. Their use carries a significant risk of neurotoxicty, for both the peripheral and central nervous system.
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Vasculitic Neuropathy: Improving Diagnostic Accuracy
SYNOPSIS: Vasculitic neuropathy is characterized by stepwise progression of sensorimotor neuropathy, usually with axonal features on electrodiagnostic studies, and often the presence of antimyeloperoxidase and rheumatoid factor antibodies and cryoglobulins. However, peripheral nerve biopsy is necessary for a definitive diagnosis.