Unexpected Issues Hinder Ethics Committees’ Effectiveness
Conflicts of interests and bloated, unfocused panels can torpedo good intentions.
Controversy Surrounds Exception from Informed Consent Enrollment
The term “exception from informed consent” for some clinical trials has been around for decades, but most patients know nothing about it. Researchers set out to explore attitudes about enrolling subjects in studies without consent.
When Hospitals Refuse to See Medicaid Patients
Serving the best interests of patients while remaining financially solvent is a high-wire act. Ethicists can help clarify a hospital’s obligations to Medicaid patients, including policies relating to admission criteria, such as for patients with inadequate funding. These policies also can clear up confusion over ethical and legal obligations to Medicaid patients who present with emergencies.
Ethical Concerns When Calling Security Is Top Tactic to Handle Agitated Patients
Police officers are not mental healthcare professionals, but often are the ones called to help a person in crisis, even if that person is in the hospital at the time. Instead, police should be teamed with a mental health professional to help de-escalate volatile situations.
U.S. Readmission Rates for TAVR
An analysis of the Nationwide Readmission Database revealed one-fifth of transcatheter aortic valve replacement patients are readmitted a median of 31 days after discharge. Medical comorbidities are the most common reason.
TAVR Outcomes in Patients on Chronic Corticosteroid Therapy
A 12-year experience with transcatheter aortic valve replacement at one Paris hospital demonstrated chronic systemic corticosteroid use increases the incidence of major 30-day complications and all-cause mortality at one year.
When Is TAVR Futile?
A study of all patients who underwent transcatheter aortic valve replacement over eight years in France was used to develop a futility score that would help predict who would not live one year after the procedure. This simple clinical score based on comorbidities predicted who would live one year with 95% specificity.
Ticagrelor in the Elderly: More Potent Platelet Inhibition Not Always Better
In a study of 14,000 elderly patients with acute myocardial infarction, treatment with ticagrelor was associated with higher risks of bleeding and all-cause death vs. clopidogrel.
Which Acute Myocardial Infarction Patients Need a Blood Transfusion?
A randomized trial of a restrictive blood transfusion strategy vs. a more liberal strategy in patients with acute myocardial infarction and anemia showed the restrictive strategy is noninferior to the liberal strategy for preventing the primary outcome of death, reinfarction, stroke, or emergency revascularization.
Pralsetinib Capsules (Gavreto)
Pralsetinib should be prescribed to treat adults with metastatic RET, fusion-positive non-small cell lung cancer.