Treatments in Oncology
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Parents, IRBs Hold Different Views on Phase I Pediatric Oncology Trials
IRB members are more likely than the public to think the risks outweigh the potential medical benefits. Parents think about the possibility of caring for a child with severe cancer and no treatment alternatives. IRBs ensure trials are ethical and that pediatric subjects are not exposed to excessive risk.
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Cancer Death Rate for Black Americans Declines, Remains Higher Than That of Other Groups
Rapid declines in deaths from lung and stomach cancers parallels rise in mortality from uterine and liver cancers.
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Unique Challenges for IRBs Evaluating Radiation Oncology Study Protocols
There may be few if any radiation oncology investigators at some institutions, and radiation therapy involves rapidly advancing technology. In light of this, IRBs might lack the necessary expertise to review these studies.
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Exploring the Cardio-Oncology Frontier
Investigators found a new cancer diagnosis was independently associated with a higher risk for cardiovascular death and nonfatal morbidity.
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Preventing Age Disparities in Cancer Trials
A leading researcher explains why patients should have equity regarding their ability to access clinical trials, to the greatest extent reasonably possible, in this Q&A.
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Decisional Capacity Is Most Common Issue in Neuro-Oncologic Ethical Consults
For a terminal condition, goals of care need to be identified so they can be honored. If discussions do not happen early, when the patient likely is at his or her peak functional status, it leaves caregivers, families, and physicians with little guidance.
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Left-Sided Breast Cancer Radiation Therapy and Coronary Artery Disease
A study of breast cancer survivors revealed left breast radiation therapy doubles the subsequent risk of coronary heart disease vs. right-sided radiation.
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Using Cardiac MRI to Detect Suspected Tumors
Among patients with suspected cardiac tumors, cardiac MRI was highly accurate at distinguishing tumor from thrombus and benign from malignant tumors, using subsequent clinical data over five years of follow-up as the diagnostic standard.
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Can Left Ventricular Strain Detect Early Cardiac Toxicity of Cancer Chemotherapy?
Using left ventricular peak systolic global longitudinal strain vs. left ventricular ejection fraction to survey patients undergoing potentially cardiotoxic chemotherapy with at least one other risk factor for heart failure showed no difference in the primary endpoint of the difference in ejection fraction between the two groups at one year.
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Relugolix Tablets (Orgovyx)
Relugolix should be prescribed to adults with advanced prostate cancer.