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<p>The revised Common Rule&rsquo;s provision that a single IRB should review protocols for multisite studies raises questions about how these IRBs handle conflicts of interest, local knowledge, and other issues. When a group of researchers sought to answer these questions, they found a big obstacle: Some IRBs, including the largest ones, were unwilling to participate.</p>

More Research Needed Into How IRBs Operate and Make Decisions

Study examines how to increase IRB transparency