Articles Tagged With: Dementia
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Predicting the Risk of Late-onset Alzheimer’s Disease and Dementia Based on Common Genetic Variants
Using a genetic risk score of 23 common genetic variants and apolipoprotein E genotype could help stratify individuals into those very likely to those very unlikely to develop late-onset Alzheimer’s disease and dementia.
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Rapid Screening for Future Risk of Parkinson’s Disease Dementia
The Montreal Parkinson Risk of Dementia Scale provides a simple eight-item screening tool with high predictive value for developing Parkinson’s disease dementia.
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Sleep Habits and the Development of Dementia
The relationship between quality of sleep and the development of dementia is controversial and not yet clearly elucidated nor understood.
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Lessons Learned From a Failed Anti-amyloid Trial for Alzheimer’s Disease
Despite the disappointing results in EXPEDITION 3, modifications of clinical trials for Alzheimer’s disease (AD) should be undertaken and trials targeting preclinical or early AD should continue with anti-amyloid agents.
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Prevalence of Cognitive Impairment in Older Women With Pelvic Floor Disorders
Mild cognitive impairment and early dementia are prevalent in women seeking care for pelvic floor disorders.
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Aerobic Exercise and Cognitive Impairment
Progressive aerobic exercise training appears to be a low-risk and effective intervention for improving cognitive function in community-dwelling adults with mild subcortical ischemic vascular cognitive impairment.
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Lifestyle Approaches to Prevent and Manage Cognitive Impairment
Despite billions of dollars in research and nearly 200 medications tested for dementia, pharmacologic treatment for Alzheimer’s disease is severely limited in effectiveness and safety. With the disappointing benefits of drug treatment, the promise of lifestyle changes to prevent and delay cognitive decline appears hopeful.
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Rehabilitation From Neurological Insults: The Role of Music-based Interventions
The authors of this comprehensive review article found evidence for the use of music-based interventions as part of rehabilitation across a broad range of neurological disorders.
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The Incidence of Dementia May Be Declining
In community-dwelling people from Bronx County, New York, there was a sharp decrease in dementia incidence in those born after mid-1929, which could not be readily explained by changes in the prevalence of cardiovascular diseases, higher education, or increased racial/ethnic diversity.
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REM Sleep, Not Slow-wave Sleep, Decreases Dementia Risk
In a series of clinical studies of cognitively normal people older than 60 years of age, disruption of REM sleep and reduced quantity of REM sleep increased the risk of developing Alzheimer-type dementia.