Articles Tagged With: Herpes
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Rehospitalization Common in Herpes Encephalitis
Herpes simplex encephalitis (HSE) is the most common cause of infectious encephalitis in the United States, accounting for around 30% of all causes of infectious encephalitis in the United States. With the advent of antiviral therapy and improved diagnostic measures, mortality and morbidity have improved over the past few decades, but patients remain at risk for long-term neurologic sequelae and even relapse.
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Herpes Vaccine Could Be Available by 2030
Early efforts to produce a protein-based vaccine for herpes failed. But a new mRNA approach has outperformed the efficacy of the past vaccines in preclinical trials and is expected to be introduced in clinical trials in the second half of 2022, investigators say. This new approach for a prophylactic genital herpes vaccine showed great promise in early studies.
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MRI Changes and Functional Outcomes Among Adults with Severe HSV Encephalitis
Herpes simplex virus is a common cause of encephalitis worldwide. When treated promptly, the mortality rate decreases from 70% to 15%, but many patients remain disabled. This multicenter cohort study analyzed magnetic resonance imaging in patients diagnosed with herpes simplex encephalitis admitted to the intensive care unit to identify factors associated with poor outcome at 90 days.
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An Investigational Vaginal Film Could One Day Prevent Pregnancy, HIV, Herpes
Researchers are studying a novel contraceptive delivery system, which uses a vaginal film to produce antibodies to sperm. The same film also could be developed to protect against HIV infection and herpes. -
Herpes Zoster Vaccine: Effective but Underused
The adjuvanted recombinant herpes zoster vaccine is highly effective in practice, but it is vastly underused.
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Infectious Disease Alert Updates
Changing Herpes Zoster Risk in Adults; Trends in Herpes Zoster Risk Among Children
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Prevalence of HSV-2 Is Falling, Data Show
Two of the most common viruses, herpes simplex virus-1 (HSV-1) and herpes simplex virus-2 (HSV-2), are steadily declining in the U.S. population.
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Sexually Transmitted Infections in Adolescents
Unfortunately, adolescents are at increased risk for sexually transmitted infections secondary to high-risk sexual behavior, victims of commercial sexual exploitation, or sexual experimentation. The consequences can be devastating in the long term. Clinicians must maintain a high degree of suspicion and sensitivity (since most teenagers are reluctant to seek medical care and may not share all the information the clinician needs) to make this diagnosis, minimize complications, and optimize outcome for this vulnerable population.
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Refining the Evaluation and Management of Neonatal Herpes Infection
Neonatal herpes infection usually presents with seizure, vesicular rash, or critical illness. The subset of infected patients without those signs were younger than two weeks of age and/or had cerebrospinal fluid pleocytosis.
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The Zoster Vaccine Rapidly Loses Effectiveness in Adults Over 60
An observational study from Kaiser Permanente Southern California showed that while the shingles vaccine reduces the risk of herpes zoster, there is a major decline in effectiveness over just eight years in older adults.