In patients with gram-negative rod bacteremia, patients receiving seven days of antibiotics had similar 90-day mortality, readmission rates, and rates of recurrent bacteremia as patients receiving 14 days of antibiotic.
Broadly classified as ergonomics in much of the world, human factors engineering ultimately may lead to changes in practices and behaviors entrenched in healthcare that endanger patients with infections and other harms.
Evidence on actual legal risks of failing to give antibiotics is lacking. Part of the problem is that both clinicians and patients frequently believe that taking an antibiotic is the safest practice in cases where it is unclear if antibiotics are needed.
While taking blood cultures should not significantly delay needed treatment, investigators noted their data prove that cultures taken post-treatment lose nearly half the clinical information needed to make subsequent treatment decisions.
Researchers analyzed the diagnostic accuracy and yield of sputum Gram stain (SGS) in community-acquired pneumonia across 24 studies of 4,533 adult patients in a meta-analysis. SGS was specific for the diagnosis of Streptococcus pneumoniae and Haemophilus influenzae infection.
The duration of parenteral antimicrobial therapy for bacteremic urinary tract infection in young infants varies between practitioners and centers. A retrospective review suggests that extending parenteral treatment beyond seven days does not alter outcomes.