Articles Tagged With: antibiotics
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Oral Antibiotics Are Noninferior to Intravenous for Bone and Joint Infections
In a randomized, controlled trial of adult patients with bone or joint infections, researchers found oral antibiotic therapy was noninferior to intravenous therapy based on treatment failure at one year.
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The Slippery Slope of Inappropriate Antibiotic Use in Children
Inappropriate antibiotic use for a child with a viral respiratory infection is not a “one and done” error. Children who receive antibiotics when diagnosed with a viral respiratory infection are more likely to seek care for viral infections subsequently and to receive inappropriate antibiotics again.
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Probiotics Do Not Prevent C. difficile Infection in Hospitalized Patients
A retrospective cohort study from a single California hospital found the administration of probiotics to patients receiving antibiotics did not reduce the incidence of healthcare facility-onset Clostridioides difficile infection.
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Infection After Placement of Antibiotic Spacers in Prosthetic Joints
Researchers reviewed a case series of 51 patients who received retained “destination spacers” after resection of infected joint prostheses. The researchers noted a significant association between the presence of preoperative sinus drainage and re-infection. Longterm antimicrobial suppression after retention of a destination spacer did not result in significant prevention of re-infections.
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Pediatric Pneumonia — Evolving Diagnosis and Management
Tachypnea has long been considered to identify which children with acute fever and cough might benefit from antibiotic treatment, especially in resource-limited parts of the world. Now, with declining rates of vaccine-preventable infections with Haemophilus influenzae and pneumococcus, new data suggest that approximately 90% of febrile, tachypneic, coughing (but still well enough for outpatient treatment) preschoolers do fine without antibiotics.
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Duration of Intravenous Antibiotic Therapy for Late-Onset Neonatal Group B Streptococcal Bacteremia
Although standard treatment of late-onset neonatal group B Streptococcus bacteremia includes intravenous antibiotic therapy for 10 days, shorter courses seem safe and effective.
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Antibiotic Decision-Making Between Medical and Surgical Teams
In an observational study conducted at an academic medical center in London, researchers looked at factors involved in decision-making. The presumptive diagnosis of infection by the emergency department (ED) influenced decision-making by both medical and surgical admitting teams. Medical teams tended to use a multidisciplinary approach to antibiotic decision-making. Surgical teams often delegated antibiotic decision-making to the most junior members of the surgical team.
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Preventing Clostridioides difficile Infections: Early De-escalation of Antipseudomonal Antibiotics
Early discontinuation of empirically administered antipseudomonal antibiotics may prevent many cases of Clostridioides difficile infection.
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Research Strides May Offer Keys to Battling Gonorrhea
Researchers are investigating a rapid test that not only checks for gonorrhea infection, but also signals if a particular strain is antibiotic-resistant. On another front, scientists report that one dose of a developmental oral antibiotic proves effective in treating uncomplicated genital infections caused by gonorrhea.
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Severe Sepsis and Septic Shock Early Management Bundle
When the Severe Sepsis and Septic Shock Early Management Bundle was used to identify patients with severe sepsis or patients in septic shock, delays in lactate measurements for patients with abnormal lactate levels were associated with delayed initiation of antibiotic therapy and increased mortality.