Articles Tagged With: antibiotics
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What Effect Do Antibiotics Have on Hormonal Contraception?
Data do not support drug interactions between hormonal contraceptives and non-rifamycin antibiotics.
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Prolonged vs. Short Duration Infusion of Beta-lactam Antibiotics: The Verdict Is In
When compared to shorter infusion duration, prolonged infusion of anti-pseudomonal β-lactam antibiotics was associated with reduced mortality.
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Which Antibiotics Are Safe in the First Trimester of Pregnancy?
A total of 7.2% of pregnant women were diagnosed with a urinary tract infection, and of these, 69% filled an antibiotic prescription. The most common antibiotics prescribed in the first trimester were nitrofurantoin, ciprofloxacin, cephalexin, and trimethoprim-sulfamethoxazole.
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Stewardship, Science, and Spirituality
Awareness of a patient’s and family’s belief system might help physicians appropriately frame explanations about the importance of antimicrobial stewardship.
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Antibiotics and Adverse Events: Doctors, Do No Harm
A retrospective study found that among 1,488 hospitalized patients who received an antibiotic, 298 (20%) experienced at least one antibiotic-associated adverse drug event. Furthermore, 287 (19%) of the antibiotic regimens were not clinically indicated, and 56 (20%) of these were associated with an adverse drug event.
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Do Antibiotics Reduce Hormonal Contraceptive Effectiveness?
This is a systematic review of studies evaluating the effect of concomitant non-rifamycin antibiotic use on hormonal contraceptive effectiveness. Although data are limited, there is no evidence to support the existence of drug interactions.
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Microbiology of Hidradenitis Suppurativa: New Evidence That Anaerobes Predominate
Using metagenomic techniques, investigators determined that two Gram-negative anaerobes, Prevotella and Porphyromonas, predominate in hidradenitis suppurativa lesions. Two others, Fusobacterium and Parvimonas, correlate with disease severity.
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Skin and Soft Tissue Infections
Skin and soft tissue infections are encountered commonly in the emergency department, presenting as a range of disorders, from uncomplicated cellulitis, impetigo, folliculitis, erysipelas, and focal abscesses to necrotizing fasciitis.
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Dual Antibiotic Therapy Is Not Routinely Necessary for Uncomplicated Cellulitis
A randomized, multicenter, placebo-controlled clinical trial that enrolled patients presenting to emergency departments with uncomplicated cellulitis found the addition of trimethoprim-sulfamethoxazole to cephalexin did not lead to better outcomes.
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Evaluation and Management of Abscesses in the Emergency Department
This article reviews the current management options for simple cutaneous abscesses in patients, including review of the epidemiology, differential diagnosis, diagnostic studies, and changing practice of wound cultures and antibiotic therapy.