Articles Tagged With: cognitive
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Cognitive Benefit of Rivastigmine in Parkinson’s Disease Dementia with Orthostatic Hypotension
Individuals with Parkinson’s disease dementia and orthostatic hypotension (OH) have more robust cognitive improvement from rivastigmine compared to those without OH. This greater response possibly is mediated by the anti-OH effect of rivastigmine.
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Nutritional Interventions in Prodromal Alzheimer’s Disease: The 36-Month LipiDiDiet Multinutrient Clinical Trial
In a randomized, double-blind, placebo-controlled trial of Fortasyn Connect (Souvenaid), a nutraceutical drink, patients with prodromal Alzheimer’s disease demonstrated, over a 36-month period, a slower decline in cognitive functions compared to the control group.
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Air Pollution and Cognitive Decline
SYNOPSIS: In this large prospective cohort study of subjects in Manhattan, researchers demonstrated an association between exposure to air pollution and decline in cognitive function over time in one cohort, but not the other.
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Can Anticoagulant Strategies Reduce Covert Brain Infarcts in Patients with Cardiovascular Disease?
Covert brain infarcts are detected on magnetic resonance imaging studies in the aging brain in about 10% of people at age 65 years, increasing to 25% at age 80 years. Most patients who develop dementia have a combination of multiple small infarcts, plus amyloid deposition. Prevention of covert infarcts is a strategy to mitigate the frequency and severity of late-life dementia.
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COVID-19 Can Cause Neurological Symptoms and Strokes in Patients
One major health problem related to COVID-19 involves neurological symptoms and signs of brain injury. Patients with COVID-19 can experience acute periods of confusion, post-traumatic amnesia, and delirium. Physicians and researchers do not know what will happen to patients with COVID-19 over the long term and whether they will fully regain their prior cognitive status.
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Mahjong and Mild Cognitive Impairment
This randomized, controlled trial notes improvement in measures of executive functioning, such as organization and planning, in elderly Chinese participants with mild cognitive impairment who were selected to play mahjong three times weekly for 12 weeks.
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Widely Used in Asia, Cilostazol Appears Effective for Long-Term Secondary Stroke Prevention
Cilostazol is a phosphodiesterase 3 inhibitor widely used in Asia for secondary stroke prevention but approved for use in North America only for symptomatic peripheral vascular disease. It has been theorized that cilostazol might be beneficial in preventing the progression of small vessel disease in the brain and, therefore, may have a secondary effect in preventing vascular dementia.
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Effects of COVID-19 on the Brain
Healthcare workers and patients who have contracted SARS-CoV-2, particularly if they were hospitalized, could be at risk of neurological deficits in the short term and as well as later cognitive problems.
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Intervention Reduces Pregnancy and STI Risk Among Young Women with Depression
Young women with depression experience a higher rate of unintended pregnancy and sexually transmitted infections than young women, in general. The challenge for family planning clinicians is to find an effective intervention to help them prevent pregnancy and maintain their health.
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Estrogen Replacement: Is Long Duration of Therapy Good for the Brain?
Longer lifetime exposure to endogenous estrogen and menopausal estrogen replacement were associated with better cognitive status in older adult women. Women who initiated estrogen therapy early (within five years of the onset of menopause) showed higher cognitive test scores than those who started later.