Articles Tagged With: efficacy
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Vaccine Challenge Trials Present Ethical Issues to IRBs, HRPPs
Bioethicists and researchers say it may be possible to shorten the typical 15-year-plus vaccine timeline through a challenge trial. In this model, participants receive the study vaccine, the are deliberately exposed to SARS-CoV-2. Safety and efficacy are important, but the risk-benefit balance for study participants is weighed more heavily in favor of the greater public good.
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Deep Brain Stimulation of the Cortico-Striato-Thalamo-Cortical Network May Be an Option for Refractory OCD
Deep brain stimulation can be a treatment option for refractory obsessive-compulsive disorder, but the results are not significantly better than lesioning procedures. Small sample sizes, diverse targets of stimulation, and inconsistencies in rating scales are limiting factors in the studies of this modality.
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Some Emergency Contraceptives Might Fail for Women with Higher BMIs
New research revealed that some emergency contraceptives might not be effective for women at higher body weights. Evidence suggests that levonorgestrel emergency contraception may have reduced effectiveness in individuals who weigh 165 pounds or more, and possibly no effectiveness for those who weigh 176 pounds or more.
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Treating Ebola Virus Infection
Two monoclonal antibody preparations have been demonstrated to significantly reduce mortality in patients with Ebola virus infection.
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Ethical Issues for Individuals Providing Unproven Stem Cell Treatments
There are well-established, significant ethical concerns regarding the safety and efficacy of treatments offered by stem cell clinics. Much less is known about those actually providing these unproven interventions. Now, researchers have collected data about their background and training.
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Benefits of On-demand Antiretroviral Pre-exposure Prophylaxis Among MSM
Might pre-exposure prophylaxis administration timed immediately before and after sexual activity, rather than daily, be effective?