Articles Tagged With: Epilepsy
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The Effect of Epilepsy on Patients with Brain Tumors
Cancer cells form direct synapses with neurons, whose electrical activity stimulates brain tumor growth. Accumulating evidence suggests that epilepsy enhances the proliferation of malignant brain tumors and that improved management of epilepsy may reduce morbidity and mortality in these patients.
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Is the Suicidality Class Warning Warranted for Antiseizure Medications?
This study reports data that refutes the U.S. Food and Drug Administration’s class warning regarding suicidality risk in patients with epilepsy who are taking the newer antiepileptics, approved since 2008. The class warning should be reconsidered.
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Efficacy and Safety of Cannabidiol in Treatment of Focal Seizures Associated with Tuberous Sclerosis Complex
Cannabidiol used as an add-on therapy for intractable focal seizures in patients with tuberous sclerosis complex was efficacious. Cannabidiol also had an acceptable adverse event profile, but frequently induced transient elevation of liver enzymes.
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Febrile and First-Time Seizures
The sudden appearance of COVID-19 has created an additional challenge to the evaluation of children with "flu-like" symptoms. This article compares and contrasts influenza and coronavirus and provides a critical update on a timely topic.
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Room for Improvement in Frontline Care of Psychogenic Nonepileptic Seizures
Psychogenic nonepileptic seizures (PNES) can be frightening and debilitating. It is not uncommon for patients suffering from PNES to present to the ED for help. However, arriving at an accurate diagnosis in these cases can be tricky. Many patients with PNES are misdiagnosed, leading to frustration, morbidity, and (in many cases) harm related to inappropriate treatment.
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Mozart Therapy for Epilepsy
A randomized, controlled, crossover trial in adult patients with drug-resistant epilepsy compared listening to a Mozart piano sonata daily to an active control. It showed reduction in seizures during the Mozart treatment compared to both baseline and the control treatment.
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Understanding Cannabidiol (CBD)
Cannabidiol is used by a growing population for many ailments. Although not typically an emergency drug, it has important interactions and a few side effects that can be seen in the emergency department.
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Epilepsy 2020: At the Crossroads of Telemedicine and Smartphone Technology
In this study, the investigators show the diagnostic value of video smartphone technology with regard to a seizure diagnosis as well as the ability of smartphone video to help distinguish epileptic seizures from nonepileptic events.
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Epilepsy Management
Epilepsy affects about 50 million people worldwide and is responsible for up to 0.5% of the global burden of disease. Although many people learn to handle their epilepsy at home, patients often are brought to the emergency department if they have a seizure in public or it is their first seizure.
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Intravenous Immunoglobulin for Treatment of Autoimmune Epilepsies
Patients with LGI1 and CASPR2 IgG-associated autoimmune epilepsy were identified and randomized to treatment with intravenous immunoglobulin (IVIG) vs. placebo. The authors hypothesized that IVIG would show superiority over placebo, with a primary endpoint of 50% or greater seizure reduction.