Articles Tagged With: therapy
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Combination Therapy of MRSA Bacteremia Was Not Beneficial in a Randomized Clinical Trial
In a randomized clinical trial conducted at 27 hospitals in four countries, researchers found that the addition of an antistaphylococcal beta-lactam to vancomycin or daptomycin (99% received vancomycin) did not lead to improved outcomes in MRSA bacteremia. The trial was stopped early because of safety concerns, including a higher risk of acute kidney injury in the combination group.
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Optimal Antithrombic Therapy After PCI for Atrial Fibrillation Patients
In three subgroups of coronary artery disease patients with atrial fibrillation, apixaban plus a P2Y12 inhibitor provided superior safety and similar efficacy outcomes as treatment with warfarin, aspirin, or both for six months.
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More Recovery Time Can Aid Patients After Hip Surgery
Research suggests some hip fracture surgery patients experience better outcomes after the procedure with a longer post-acute stay. Recovery also is easier when these patients do not have to engage in intensive physical therapy initiated immediately after surgery.
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Neuraminidase Inhibitors Reduce Hospital Length of Stay in Patients With Clinically Suspected or Laboratory-Confirmed Influenza A
A meta-analysis that included more than 18,000 patients from 70 clinical centers in 36 countries found that neuraminidase inhibitors started at the beginning of hospitalization in patients with clinically suspected or laboratory-confirmed influenza A reduced the length of hospitalization by 19%.
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Management of Nontraumatic Intracranial Emergencies: A Clinical Update
This article attempts to provide evidence-based, practical guidelines to the frontline clinician in the nontrauma intensive care setting.
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Menopausal Hormonal Therapy and Breast Cancer Risk: Are Old Data Relevant to Today’s Practice?
An individual-participant meta-analysis of prospective studies revealed menopausal hormone therapy associated with an elevation in the risk of breast cancer, with the highest risks associated with daily combined therapy.
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Researchers Testing Stem Cell Therapy for Multiple Sclerosis
NIH is funding a comparison of FDA-approved drugs against experimental stem cell approach.
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Estrogen Replacement: Is Long Duration of Therapy Good for the Brain?
Longer lifetime exposure to endogenous estrogen and menopausal estrogen replacement were associated with better cognitive status in older adult women. Women who initiated estrogen therapy early (within five years of the onset of menopause) showed higher cognitive test scores than those who started later.
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CRT Nonresponders Experience Poor Outcomes, Warrant More Aggressive Management
The ADVANCE CRT registry revealed a significant minority of patients fail to respond to cardiac resynchronization therapy, conferring a worse prognosis.
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Menopausal Hormonal Therapy and Breast Cancer Risk: Are Old Data Relevant to Today’s Practice?
An individual-participant meta-analysis of prospective studies found menopausal hormone therapy associated with an elevation in the risk of breast cancer, with the highest risks associated with daily combined therapy.