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  • Opill Rollout Includes Major Pharmacies and Retailers — but Price Tag Needs Work

    The rollout of the nation’s first over-the-counter birth control pill, Opill, is a major step toward improving contraception access across the United States. But some obstacles remain, including cost and access for minors in places hostile to reproductive autonomy.

  • What Are Those T Waves?

    The patient whose ECG appears in the figure presented to an ambulatory care clinic for chest pain. Is the patient likely to have hyperkalemia?

  • Iloprost Injection (Aurlumyn)

    The U.S. Food and Drug Administration has approved iloprost for the treatment of severe frostbite to reduce the risk of amputation of fingers or toes. Iloprost, a synthetic analog of prostaglandin, initially was approved in 2004 for the treatment of pulmonary arterial hypertension. For that indication, it was given a priority review, accelerated approval, breakthrough therapy, and orphan drug designations. Iloprost for the frostbite indication is distributed by Eicos Sciences as Aurlumyn.

  • Empowered Relief vs. CBT vs. Health Education for Low Back Pain

    This randomized clinical trial involving adults with chronic low back pain demonstrates that a single session of a pain management class, when compared to a full course of cognitive behavioral therapy, yields noninferior (clinically on par) outcomes in pain catastrophizing and several other measures at the three-month follow-up.

  • Rates of Ad Hoc PCI Higher for Multivessel and Left Main Diseases

    In this retrospective analysis of patients from the New York state percutaneous coronary intervention (PCI) and coronary artery bypass grafting databases, ad hoc PCI was performed frequently among patients with left main and multivessel disease. Also, variability in ad hoc PCI use among hospitals and physicians for these populations was high.

  • How Safe Is Cannabis for the Heart?

    A nationwide Danish study of new prescriptions for medical cannabis for chronic pain compared to control patients has found that the 180-day incidence of atrial fibrillation/flutter is two-fold higher, but the absolute number of arrhythmias is small.

  • H. pylori Infection: A Warning Sign for Alzheimer’s Dementia

    A large nested case-control cohort study of subjects aged 50 years and older found that clinically apparent Helicobacter pylori infection is associated with a moderately increased risk of developing Alzheimer’s disease.

  • Quality, not Quantity: Plant-Based Carbs Might Result in Less Weight Gain

    This long-term prospective study found that adults on low-carbohydrate diets rich in plant-based and whole grain sources of protein and fat experienced significantly less weight gain than those on other types of low-carbohydrate diets.

  • Food as Medicine? Follow the Evidence

    In this randomized, controlled study of more than 400 individuals with uncontrolled type 2 diabetes and food insecurity, an intensive intervention offering healthy groceries and educational efforts failed to significantly affect glycemic control but resulted in heightened engagement with preventive healthcare services in the intervention group compared to the control.

  • The Silent Epidemic: Hepatitis C Virus

    Hepatitis C accounts for a significant burden of disease. There are many barriers to the eradication of hepatitis C virus (HCV), from infection identification to treatment, making it a very complex public health concern. Unfortunately, no vaccine for HCV exists yet, and development proves difficult because of the overwhelming genetic diversity. HCV can be treated by a patient’s primary care physician; this group is instrumental in screening for and treating hepatitis C.