Critical Care Alert
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Vasopressin and Steroids Increase Likelihood of Return of Spontaneous Circulation with Unclear Longer-Term Effects
In this multicenter, randomized clinical trial, the combination of vasopressin and methylprednisolone improved the rate of return of spontaneous circulation in patients with in-hospital cardiac arrest but had no significant effect on longer-term outcomes.
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Practice Guidelines for Difficult Airways
The American Society of Anesthesiologists has released updated guidelines on the management of the difficult airway.
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Efficacy of Neuroinvasive Goal-Directed Therapy in Hypoxic Ischemic Brain Injury After Cardiac Arrest
This retrospective observational study found the suggestion of favorable neurological outcomes at six months among out-of-hospital cardiac arrest patients who received interventions to optimally manage intracranial pressure and brain tissue oxygenation compared to standard care.
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An Assessment of Hospital-Acquired Infections in Critically Ill SARS-CoV-2-Infected Patients
This retrospective analysis of prospectively collected data showed that critically ill patients with SARS-CoV-2 infection are at increased risk for hospital-acquired infections.
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Treatment and Follow-Up of Acute Pulmonary Embolism: A Multidisciplinary Team Approach
This article will review management of pulmonary embolism based on risk stratification, with an emphasis on the role of a Pulmonary Embolism Response Team as well as appropriate follow-up.
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Medicare Sepsis Performance Measure Criteria Do Not Improve Outcomes
A longitudinal study of a single health system’s adherence to and outcomes of Medicare Sepsis Performance Measures (SEP-1) did not show an improvement in mortality despite improvements in adherence to guideline-mandated care.
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Attitudes Toward Hyperoxemia and Oxygen Therapy Among Nurses, Respiratory Therapists, and Physicians
Critical care clinicians, such as nurses, respiratory therapists, and physicians, have varying opinions regarding oxygen therapy and hyperoxia. Interdisciplinary education addressing current evidence of oxygen therapy and the potentially harmful effects of oxygen is warranted.
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Burnout in the Critical Care Workforce
The burnout epidemic has plagued the medical profession for decades, with an escalating prevalence most recently fueled by the COVID-19 pandemic.
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Is There a Role for Intermediate-Dose Anticoagulation for Critically Ill COVID-19 Patients?
In a multicenter, randomized clinical trial of critically ill COVID-19 patients, intermediate-dose compared to standard-dose prophylactic anticoagulation did not result in significant differences in the rates of venous or arterial thrombosis, treatment with extracorporeal membrane oxygenation, or mortality within 30 days.
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Dexmedetomidine for Sedation in Patients Undergoing Mechanical Ventilation in the ICU
This special feature will focus on dexmedetomidine as a sedative for invasive mechanical ventilation in the ICU.