Head Trauma
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Are Women More Prone to Brain Injury Than Men When Playing Soccer?
Repeated subconcussive injuries to the brain, such as “heading” the ball in soccer, result in more severe injury and slower recovery in women compared to men.
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Hypercapnic Acidosis and Clinical Outcomes in Patients With Acute Brain Injury
In this multicenter retrospective study, hypercapnic acidosis was associated with worse clinical outcomes in mechanically ventilated patients with acute brain injury.
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What Are the Early Predictors for Post-traumatic Epilepsy After Injury?
Following traumatic brain injury, early (first five days after injury) epileptiform abnormalities on EEG were seen more commonly in patients with subsequent post-traumatic epilepsy (PTE), compared to controls, and were found to be a significant and independent predictor of PTE. The presence of subdural hemorrhage was the only other independent predictor of PTE.
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Intracranial Pressure Changes in Mild Traumatic Brain Injury
After an exhaustive review of the animal and human studies literature regarding mild traumatic brain injury (mTBI), Haider et al. did not reach consistent conclusions regarding evidence for intracranial pressure elevation in human patients who sustain an mTBI.
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Prediction of Persistent Post-concussion Symptoms After Mild Traumatic Brain Injury
Persistent post-concussion syndrome may last for more than six months, and risk factors include female sex, neck pain, headache, and post-concussive symptoms at two weeks after the injury.
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Salivary microRNA as Biomarker to Predict Prolonged Concussion Symptoms
In a prospective cohort study of pediatric patients, aged 7 to 21 years, diagnosed with concussion, salivary microRNAs were found to be a potential biomarker for predicting prolonged concussion symptoms.
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TBI in Prodromal Parkinson’s Disease
This population-based study using Medicare data demonstrated that in the five years prior to diagnosis of Parkinson’s disease (PD), when compared with age-matched controls, those who were diagnosed with PD had a higher incidence of traumatic brain injury (TBI). The TBI was rated as mild and concussive and was most often related to falls.
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Optimizing Brain Oxygen in Severe Traumatic Brain Injury
In a Phase II, single-blind, randomized, multicenter trial, the use of intraparenchymal brain tissue oxygenation monitoring reduced brain tissue hypoxia in patients with severe traumatic brain injury.
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Childhood Head Trauma and Risk of Subsequent Diagnosis of Multiple Sclerosis
A large study that reviewed longitudinally collected data from the national Swedish Patient Register found that head trauma in adolescents was associated with an increased risk of subsequent diagnosis of multiple sclerosis.
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Tau as a Biomarker of Acute and Chronic Traumatic Brain Injury
The ongoing search for reliable biomarkers of traumatic brain injury repeatedly has demonstrated the reliability of using plasma phosphor-tau levels to help distinguish injury from normal, and severe injury from mild injury.