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In an analysis of outcomes for patients treated at M.D. Anderson for metastatic renal cell carcinoma before and since the advent of treatment with tyrosine kinase inhibitors (TKI), the development of brain metastases was shown to be significantly reduced. The authors speculate that TKI treatment is altering the natural history of renal carcinoma.
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There have been reports over the past decade of an interesting inverse association between allergy and glioma. In the current report pooling data from four large cohorts, investigators examined (prediagnostic) immunoglobulin E levels in 169 individuals who were to develop glioma and compared these with levels in 520 matched controls.
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A 61-year-old female was evaluated for intermittent upper abdominal discomfort. A non-contrast enhanced CT revealed 5x3x4 cm lesion in the spleen that appeared to be cystic.
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Capitalizing on a large cohort of British patients followed after treatment for Hodgkin's lymphoma, the risk of occurrence of second malignancy was assessed in the context of treatment with chemotherapy alone vs treatment with combined chemotherapy and radiation.
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New recommendations for HPV vaccine; guidelines for treatment of essential tremor; updates on smoking cessation drugs; and FDA actions.
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A 66-year-old postmenopausal retired teacher went to her primary care physician because she found a lump in her right breast during a routine bath.
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From a large cohort of women followed prospectively and with an adjunct meta-analysis of existing evaluable studies, a clearly demonstrated, nearly universal (i.e., across tumor types) incremental increase in cancer incidence was observed with advancing height.
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Medication poisonings in children; rosuvastatin vs atorvastatin for atherosclerosis; saw palmetto for prostate symptoms; using atypical antipsychotics for off-label indications in adults; and FDA actions.
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