Multiple Sclerosis
RSSArticles
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Biomarkers of Intrathecal Inflammation in Multiple Sclerosis and Other Disorders
A study of intrathecal immune markers in neuro-immunological diseases revealed increased numbers of activated T and B cells in both relapsing and progressive multiple sclerosis, but they were preferentially embedded in the brain tissue in progressive multiple sclerosis.
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Autologous Hematopoietic Stem Cell Transplant for Relapsing-Remitting MS
Interim analysis at 3 years post-treatment of a study of high-dose immunosuppression and autologous hematopoietic stem cell transplant for relapsing remitting-multiple sclerosis demonstrates sustained disease control but also shows potential risks associated with this treatment.
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Is Pediatric-onset Multiple Sclerosis a Neurodegenerative Disorder?
ABSTRACT & COMMENTARY: Pediatric-onset multiple sclerosis compromises age-expected brain growth.
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Surgical Treatment of Brain Metastases
Surgical removal of brain metastases remains an important part of palliative therapy for metastatic cancer. -
Women with Migraine: Options for Decreasing Disability
Menstrually related migraine is difficult to treat and options are limited. Hormonal manipulation is controversial and unproven. -
Teriflunomide: A New Oral Agent for the Treatment of Multiple Sclerosis
Teriflunomide, an orally administered inhibitor of dihydro-orotate dehydrogenase, was found to be superior to placebo in reducing relapses in a 2-year, Phase 3 clinical trial in patients with multiple sclerosis. -
Clinical Briefs in Primary Care Supplement
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Stroke Alert: A Review of Current Clinical Stroke Literature
Forty-nine clinical centers and 18 positron emission tomography (PET) centers in the United States and Canada participated in a randomized, blinded-adjudication clinical treatment trial of 195 patients with symptomatic atherosclerotic internal carotid artery occlusion (AICAO) who also had hemodynamic cerebral ischemia identified by ipsilateral increased oxygen extraction fraction measured by PET. -
Pharmacology Watch
New recommendations for HPV vaccine; guidelines for treatment of essential tremor; updates on smoking cessation drugs; and FDA actions. -
Rituximab May Be Effective for Refractory Myasthenia Gravis
In a restrospective review, rituximab appeared beneficial for patients with medication-resistant myasthenia gravis.