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In a case-control study, older patients who received an angiotensin converting enzyme inhibitor or an angiotensin receptor blocker along with co-trimoxazole had an increased risk of sudden death (unadjusted odds ratio 1.83, 95% confidence interval 1.50 to 2.24). Hyperkalemia is hypothesized to be the underlying mechanism.
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In the fifth and sixth decades of the 20th century, Charles Smith reported the results of skin testing with coccidioidin, a culture filtrate of the mycelial phase of Coccidioides.
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Meningitis is very unlikely in otherwise healthy-appearing febrile infants older than 21 days of age. Thus, cerebrospinal fluid analysis might not be needed as part of a “routine” evaluation of these babies.
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Nationally, nonblack children with otitis media more frequently receive broad-spectrum antibiotics than black children do. The majority of children with otitis media in the United States receive inappropriate treatment with broad-spectrum antibiotics.
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The immunogenicity of trivalent influenza vaccine is attenuated by the administration of A(H1N1)pdm09 4 months before, an effect partially overcome by the presence of an adjuvant in the former.
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In a single academic medical center, changing from a strategy of prior authorization to prospective audit with feedback led to significantly increased total antibiotic use and use of agents with a broad spectrum of gram-negative activity.
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Hospital infection control policies for the management of suspect or documented Ebola Virus disease (EVD) should give consideration to appropriate triage procedures for their labor and delivery units.
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Helicobacter and Your Gallbladder; Warning: Can Gardening be Hazardous to Your Health?; Sylvester Shares His Salmonella; Combination Therapy for Bacterial Endocarditis
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The following summary of selected abstracts from 3 meetings will be published in multiple parts. The 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) met in Chicago September 14-17, 2003. The Infectious Disease Society of America (IDSA) met in San Diego October 9-12, 2003.